Table 1 General features, clinical characteristics, and psychological status of patients with IBS alone and those of patients with overlapping IBS-GERD
Characteristics | All patients (n = 341) | Patients with IBS alone (n = 244) | Patients with overlapping IBS-GERD(n = 97) | p-value |
|---|---|---|---|---|
General features | Â | Â | Â | Â |
Age, years (mean ± SD) | 50.39 ± 13.48 | 49.34 ± 13.65 | 53.04 ± 12.71 | 0.022 |
Gender, n (%) | Â | Â | Â | 0.101 |
 Male | 136(39.9) | 104(42.6) | 32(33.0) |  |
 Female | 205(60.1) | 140(57.4) | 65(67.0) |  |
Nation, n (%) | Â | Â | Â | 0.874 |
 The Han nationality | 321(94.1) | 230(94.3) | 91(93.8) |  |
 Non-Han | 20(5.9) | 14(5.7) | 6(6.2) |  |
Educational status, n (%) | Â | Â | Â | 0.147 |
 Below high school | 104(30.5) | 67(27.5) | 37(38.1) |  |
 High school | 91(26.7) | 69(28.3) | 22(22.7) |  |
 Above high school | 146(42.8) | 108(44.3) | 38(39.2) |  |
Marital status, n (%) | Â | Â | Â | 0.490 |
 Unmarried, widowed, or divorced | 38(11.1) | 29(11.9) | 9(9.3) |  |
 Be married | 303(88.9) | 215(88.1) | 88(90.7) |  |
Smoking status, n (%) | Â | Â | Â | 0.542 |
 Never smoker | 281(82.4) | 198(81.1) | 83(85.6) |  |
 Current smoker | 34(10.0) | 27(11.1) | 7(7.2) |  |
 Former smoker | 26(7.6) | 19(7.8) | 7(7.2) |  |
Alcohol consumption, n (%) | Â | Â | Â | 0.536 |
 Never drinker | 264(77.4) | 192(78.7) | 72(74.2) |  |
 Current drinker | 38(11.1) | 27(11.1) | 11(11.3) |  |
 Former drinker | 39(11.4) | 25(10.2) | 14(14.4) |  |
Permanent residence, n (%) | Â | Â | Â | 0.515 |
 Urban | 281(82.4) | 199(81.6) | 82(84.5) |  |
 Rural | 60(17.6) | 45(18.4) | 15(15.5) |  |
Clinical characteristics | Â | Â | Â | Â |
Duration of disease (years), median (IQR) | 2.0(1.0–4.0) | 2.0(1.0–4.0) | 2.0(1.0-4.5) | 0.644 |
Source of cases, n (%) | Â | Â | Â | 0.111 |
 Outpatient | 178(52.2) | 134(54.9) | 44(45.4) |  |
 Ward | 163(47.8) | 110(45.1) | 53(54.6) |  |
IBS subtypes, n (%) | Â | Â | Â | 0.583 |
 IBS with predominant constipation | 91(26.7) | 69(28.3) | 22(22.7) |  |
 IBS with predominant diarrhea | 147(43.1) | 106(43.4) | 41(42.3) |  |
 IBS with mixed bowel habits | 62(18.2) | 41(16.8) | 21(21.6) |  |
 IBS Unclassified | 41(12.0) | 28(11.5) | 13(13.4) |  |
Psychological status | Â | Â | Â | Â |
PSI Stress(Mean ± SD) | 1.99 ± 2.06 | 1.89 ± 2.11 | 2.27 ± 1.9 | 0.106 |
PSI Well-being(Mean ± SD) | 4.41 ± 1.5 | 4.56 ± 1.46 | 4.03 ± 1.55 | 0.003 |
PSI Psychological Distress (Mean ± SD) | 4.62 ± 2.94 | 4.35 ± 2.98 | 5.31 ± 2.73 | 0.005 |
PSI Abnormal Illness Behavior (Mean ± SD) | 1.8 ± 1.66 | 1.7 ± 1.58 | 2.06 ± 1.83 | 0.069 |
PSI Quality of Life (Mean ± SD) | 2.5 ± 0.77 | 2.5 ± 0.76 | 2.48 ± 0.79 | 0.832 |
PSSS total score (Mean ± SD) | 14.68 ± 11.21 | 12.73 ± 10.42 | 19.59 ± 11.68 | < 0.001 |
WHO-5 Well-being Index (Mean ± SD) | 53.16 ± 27.88 | 55.1 ± 27.7 | 48.29 ± 27.87 | 0.042 |
Euthymia Scale score (Mean ± SD) | 7.74 ± 2.55 | 8 ± 2.41 | 7.09 ± 2.78 | 0.005 |
PHQ-9 score (Mean ± SD) | 5.96 ± 5.18 | 5.12 ± 4.76 | 8.08 ± 5.6 | < 0.001 |
GAD-7 score (Mean ± SD) | 4.91 ± 4.75 | 4.24 ± 4.46 | 6.59 ± 5.08 | < 0.001 |