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Table 1 Demographic characteristics and serum chemistries of the study participants

From: Characteristics of serum bile acid profiles among individuals with metabolic dysfunction-associated steatotic liver disease

 

CON (n = 49)

MASLD (n = 215)

t/Z/χ2

p-value

Age, years

48.1 (42.7, 54.2)

51.4 (45.2, 56.5)

− 2.095

0.054

Female, n (%)

22 (44.9%)

76 (35.3%)

1.303

0.212

Asian, n (%)

49 (100%)

215 (100%)

Height, cm

170.0 (162.5, 174.8)

170.0 (163.2, 174.0)

− 0.167

0.964

Weight, Kg

70.0 (59.3, 75.0)

70.0 (62.0, 80.0)

− 1.607

0.075

BMI, kg/m2

23.7 (21.2, 25.5)

24.8 (22.6, 26.7)

− 2.625

0.008

Overweight/obese, n (%)

21 (42.9%)

153 (71.2%)

14.230

 < 0.001

ALT, U/L

20.0 (15.0, 24.5)

25.0 (17.0, 40.0)

− 2.93

0.005

AST, U/L

22.0 (18.5, 27.5)

22.0 (18.0, 28.0)

− 0.778

0.486

GGT, U/L

24.0 (18.0, 37.5)

30.0 (19.0, 48.0)

− 1.867

0.077

TBIL, umol/L

12.0 (9.0, 14.5)

12.0 (9.0, 16.0)

− 0.232

0.762

DBIL, umol/L

3.0 (2.0, 4.0)

3.1 (2.0, 4.6)

− 0.499

0.547

TG, mmol/L

1.3 (0.9, 1.8)

1.6 (1.1, 2.4)

− 2.783

0.005

TC, mmol/L

4.5 (3.8, 5.2)

4.9 (4.4, 5.4)

− 2.775

0.006

HDL-C, mmol/L

1.5 (1.2, 1.9)

1.4 (1.2, 1.7)

− 2.239

0.025

LDL-C, mmol/L

2.9 (2.1, 4.0)

3.1 (2.5, 3.6)

− 1.007

0.314

ALB, g/L

46.9 (45.1, 48.5)

46.2 (44.4, 47.8)

− 1.404

0.178

FBG, mmol/L

4.6 (4.4, 5.5)

5.3 (4.8, 6.8)

− 4.911

 < 0.001

CR, umol/L

73.1 (14.9)

68.4 (16.9)

1.799

0.073

UA, umol/L

331.0 (279.5, 398.0)

342.0 (276.0, 416.0)

− 0.559

0.587

  1. Abbreviations: Mean ± SD、n (%) or median (interquartile range), overweight/obese defined as BMI ≥ 24. BMI body mass index, ALT Alanine aminotransferase, AST aspartate aminotransferase, GGT Gamma glutamyl transpeptidase, TBIL Total bilirubin, DBIL Direct Bilirubin, TG Triglyceride, TC Total Cholesterol, HDL-C High-Density lipoprotein cholesterol, LDL-C Low-Density Lipoprotein Cholesterol, ALB Albumin, FBG Fasting blood glucose, CR Creatinine, UA Uric Acid