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Table 3 Variables significantly associated with time to therapy (TTT) in univariate and multivariate analyses

From: Prolonged time to treatment of biologics in inflammatory bowel disease: disparities from a retrospective study in a tertiary referral centre in the UK

Baseline data

Univariate analysis

Multivariate analysis

 

Relative ratio (95% CI)

p-value

Relative ratio (95% CI)

p-value

Age at referrala

1.03 (0.99–1.07)

0.14

  

Ethnicity

 Asian or Pakistani

1

0.007

1

0.01

 White British

1.18 (1.04–1.34)

 

1.13 (1.00–1.28)

 

 Other ethnic group

1.40 (1.08–1.81)

 

1.41 (1.10–1.80)

 

IBD type

 UC ( +)

1

0.02

1

0.02

 CD

1.16 (1.03–1.32)

 

1.18 (1.03–1.34)

 

Completed funding application

 Yes

1

0.07

1

0.06

 No

1.15 (0.99–1.34)

 

1.15 (1.00–1.33)

 

Biologic drug

 Infliximab

1

0.008

1

0.001

 Adalimumab

1.24 (105–1.46)

 

1.25 (1.06–1.46)

 

 Vedolizumab

1.02 (0.87–1.18)

 

1.00 (0.86–1.19)

 

 Ustekinumab

0.91 (0.75–1.10)

 

0.86 (0.71–1.04)

 
  1. ( +) Including IBD-unclassified patients
  2. Abbreviations: CI confidence interval, CD Crohn’s disease, UC ulcerative colitis
  3. a Odds ratio given for a 10-year increase in age at referral or diagnosis