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Table 1 Clinical and biochemical characteristics of study subjects and the differences of factors between patients with high and low SUA levels by gender

From: Gender difference in the association between serum uric acid and metabolic dysfunction-associated steatotic liver disease in patients with newly diagnosed type 2 diabetes

General Indexes

Males(n = 656)

Females(n = 431)

Low SUA group

High SUA group

P value

Low SUA group

High SUA group

P value

Age(yr)

49.04 ± 11.71

42.08 ± 13.02

 < 0.001*

52.5 ± 12.35

48.6 ± 14.12

0.002*

BMI(kg/m2)

25.13 ± 3.43

28.38 ± 3.92

 < 0.001*

25.6 ± 4.55

27.04 ± 4.32

0.001*

SBP(mmHg)

131.81 ± 16.26

138.31 ± 16.31

 < 0.001*

133.61 ± 18.42

138.4 ± 17.99

0.007*

DBP(mmHg)

82.55 ± 11.09

87.55 ± 11.63

 < 0.001*

81.28 ± 11.71

84.3 ± 11.58

0.007*

ALT (IU/L)

22.6 (16.9–31)

34.8 (24.1–60.35)

 < 0.001*

19 (14–27)

26.3 (16.85–44.78)

0.001*

AST (IU/L)

21 (17–26)

26.2 (21.95–43.5)

 < 0.001*

19.1 (15.62–25.07)

25.9 (19–34.6)

0.001*

γ-GGT (IU/L)

31 (22–44.1)

43 (33–73.1)

 < 0.001*

22.1 (16–38)

29.8 (20.85–47.18)

0.005*

FBG(mmol/L)

9.61 ± 3.15

10.02 ± 3.97

0.14

9.52 ± 3.63

9.97 ± 3.96

0.235

TC(mmol/L)

4.9 ± 1.24

5.45 ± 1.42

 < 0.001*

5.22 ± 1.89

5.51 ± 1.61

0.027*

TG(mmol/L)

1.42 (0.96–2.21)

2.36 (1.45–4.07)

 < 0.001*

1.29 (0.93–1.91)

1.81 (1.21–2.46)

 < 0.001*

LDL(mmol/L)

3.11 ± 0.83

3.32 ± 0.87

0.001*

3.33 ± 0.84

3.40 ± 0.94

0.445

HDL(mmol/L)

1.09 ± 0.22

1.09 ± 0.32

0.87

1.26 ± 0.29

1.22 ± 0.39

0.284

BUN(mmol/L)

5.51 ± 1.47

5.49 ± 1.54

0.84

4.85 ± 1.44

5.17 ± 1.98

0.053

Cr(µmol/L)

67.07 ± 12.57

71.65 ± 18.04

 < 0.001*

49.56 ± 11.31

55.63 ± 24.95

0.001*

Prevalence rate of MASLD

55.96%

88.14%

 < 0.001*

65.11%

80.55%

 < 0.001*

  1. For males, low SUA group: SUA < 335 µmol/L, high SUA group: SUA ≥ 335 µmol/L. For females, low SUA group: SUA < 280 µmol/L, high SUA group: SUA ≥ 280 µmol/L. SBP: systolic pressure, DBP: diastolic pressure, ALT: alanine aminotransferase; AST: aspartate aminotransferase; γ-GGT: gamma-glutamyl transferase. FBG: fasting blood glucose, TC: total cholesterol, TG: triglycerides, LDL: low-density lipoprotein, HDL: high-density lipoprotein, BUN: blood urea nitrogen, Cr: creatinine; *P < 0.05 was considered a statistically significant difference