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Table 1 Weighted characteristics of the study population based on NAFLD

From: The role of C-reactive protein to lymphocyte ratio in NAFLD and mortality among NAFLD patients

Characteristic2

N

Overall N = 111,700,8551

Non-NAFLD N = 58,533,7211

NAFLD N = 53,167,1341

p-value

Age (years)

4371

   

< 0.001

 20–39

 

1403 (34%)

873 (41%)

530 (26%)

 

 40–60

 

1493 (37%)

672 (33%)

821 (42%)

 

 > 60

 

1475 (30%)

689 (27%)

786 (33%)

 

Gender

4371

   

< 0.001

 Male

 

2187 (49%)

1013 (42%)

1174 (56%)

 

 Female

 

2184 (51%)

1221 (58%)

963 (44%)

 

Race and ethnicity

4371

   

0.002

 Mexican American

 

547 (6.6%)

231 (5.5%)

316 (7.9%)

 

 Other Hispanic

 

427 (5.3%)

196 (5.1%)

231 (5.4%)

 

 Non-Hispanic White

 

1666 (69%)

834 (69%)

832 (69%)

 

 Non-Hispanic Black

 

1002 (10%)

509 (10%)

493 (11%)

 

 Other Race

 

729 (8.5%)

464 (9.8%)

265 (7.0%)

 

PIR

4371

   

0.7

 < 1.0

 

616 (9.2%)

323 (9.3%)

293 (9.0%)

 

 1.0–3.0

 

1829 (33%)

894 (32%)

935 (33%)

 

 > 3.0

 

1926 (58%)

1017 (59%)

909 (58%)

 

Educational level

4371

   

< 0.001

 < High school

 

586 (7.6%)

272 (6.5%)

314 (8.7%)

 

 = High school

 

903 (21%)

429 (19%)

474 (23%)

 

 > High school

 

2882 (72%)

1533 (75%)

1349 (68%)

 

BMI

4371

   

< 0.001

 < 18.5

 

56 (1.3%)

56 (2.5%)

0 (0%)

 

 18.5–24.9

 

1130 (27%)

1105 (50%)

25 (0.9%)

 

 25.0–29.9

 

1402 (31%)

907 (40%)

495 (21%)

 

 ≥ 30.0

 

1783 (41%)

166 (7.0%)

1617 (78%)

 

Hypertension

4371

   

< 0.001

 No

 

2061 (52%)

1337 (65%)

724 (37%)

 

 Yes

 

2310 (48%)

897 (35%)

1413 (63%)

 

Diabetes

4371

   

< 0.001

 No

 

3565 (86%)

2018 (94%)

1547 (77%)

 

 Yes

 

806 (14%)

216 (5.9%)

590 (23%)

 

Smoking status

4371

   

0.006

 Never

 

2550 (59%)

1378 (62%)

1172 (57%)

 

 Current

 

1129 (27%)

486 (24%)

643 (31%)

 

 Former

 

692 (13%)

370 (14%)

322 (12%)

 

CVD

4371

   

< 0.001

 Yes

 

428 (7.5%)

154 (5.0%)

274 (10%)

 

 No

 

3943 (92%)

2080 (95%)

1863 (90%)

 

Dyslipidemia

4371

   

< 0.001

 No

 

1281 (30%)

913 (42%)

368 (17%)

 

 Yes

 

3090 (70%)

1321 (58%)

1769 (83%)

 

ALT (U/L)

4371

23 ± (15)

19 ± (10)

28 ± (17)

< 0.001

AST (U/L)

4371

23 ± (10)

22 ± (9)

24 ± (11)

< 0.001

HDL-C (mg/dl)

4371

56 ± (18)

62 ± (18)

48 ± (13)

< 0.001

TG (mg/dl)

4371

146 ± (133)

102 ± (52)

194 ± (172)

< 0.001

TC (mg/dl)

4371

194 ± (42)

189 ± (40)

198 ± (44)

< 0.001

UA (mg/dl)

4371

5.35 ± (1.39)

4.92 ± (1.24)

5.82 ± (1.39)

< 0.001

Physical activity

4371

   

< 0.001

 Inactive

 

1485 (30%)

666 (24%)

819 (36%)

 

 Moderately active

 

449 (10.0%)

228 (10.0%)

221 (9.9%)

 

 Highly active

 

2437 (60%)

1340 (66%)

1097 (54%)

 

CLR(mg/cells*10–9)

4371

1.79 ± (3.93)

1.28 ± (4.03)

2.36 ± (3.73)

< 0.001

CLR quartile3

4371

   

< 0.001

 Q1

 

1068 (25%)

823 (37%)

245 (12%)

 

 Q2

 

1029 (25%)

593 (28%)

436 (21%)

 

 Q3

 

1145 (25%)

484 (21%)

661 (30%)

 

 Q4

 

1129 (25%)

334 (14%)

795 (38%)

 
  1. Abbreviations PIR ratio of family income to poverty, BMI body max index, CVD cardiovascular disease, ALT alanine aminotransferase, AST aspartate aminotransferase, HDL cholesterol, high-density lipoprotein cholesterol, TG triglyceride, TC total cholesterol, UA uric acid, CLR ratio of C-reactive protein to lymphocytes
  2. 1N: Weighted population
  3. 2Mean ± (SD) for continuous variables: P value was calculated by design-based KruskalWallis test; % for categorical variables: P value was calculated by Pearson's X^2: Rao & Scott adjustment
  4. 3Q1–Q4 indicates quartile 1–quartile 4