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Table 2 Predictive factors for distinguishing gastric gists from leiomyomas

From: Diagnostic accuracy and influencing factors of microprobe endoscopic ultrasound for gastrointestinal subepithelial lesions: a multicenter retrospective study

Variable

GIST [n (%)]

Leiomyoma [n (%)]

Univariate analysis

Multivariate analysis a)

OR (95% CI)

P value

OR (95% CI)

P value

Sex

      

 Male

99 (36.94)

35 (26.51)

1[Reference]

 

1[Reference]

 

 Female

169 (63.06)

97 (73.48)

0.62(0.39–0.96)

0.039b)

0.75(0.44–1.28)

0.288

Age (year)

      

 ≤ 55

94

89

1 [Reference]

 

1 [Reference]

 

 >55

174

43

3.83(2.46–5.96)

<0.001b)

3.05(1.86-5.00)

<0.001b)

Lesion location

      

 Upper third of stomach

161 (60.07)

61 (46.21)

1 [Reference]

 

1 [Reference]

 

 Middle third of stomach

100 (37.31)

70 (53.03)

0.54(0.35–0.83)

0.005b)

0.58(0.36–0.96)

0.033b)

 Lower third of stomach

7 (2.61)

1 (0.76)

2.65(0.32–22.01)

0.366

1.57(1.15–16.19)

0.710

Lesion size (cm)

      

 <2.0

208(77.61)

122(92.42)

1 [Reference]

 

1 [Reference]

 

 ≥2.0

60(22.39)

10(7.58)

3.52(1.74–7.13)

<0.001b)

3.45(1.51–7.88)

0.003b)

Originating layer

      

 Deep mucosa

2 (0.75)

1 (0.76)

1 [Reference]

   

 Muscularis mucosa

1 (0.37)

2 (1.52)

0.25(0.01–7.45)

0.423

  

 Submucosa

12 (4.48)

4 (3.03)

1.50(0.11–21.31)

0.765

  

 Muscularis propria

253 (94.40)

125 (94.70)

1.01(0.09–11.27)

0.992

  

Echogenicity

      

 Non-hypoechoic

8 (2.99)

0

1 [Reference]

   

 Hypo-echoic

260 (97.01)

132 (100.00)

0.00(0.00–0.00)

0.999

  

Echo heterogeneity

      

 Homogeneous

175 (68.09) c)

119 (98.35) c)

1 [Reference]

 

1 [Reference]

 

 Inhomogeneous

82 (31.90)

2 (1.65)

27.88(6.73-115.56)

<0.001b)

20.77(4.93–87.52)

<0.001b)

  1. GIST, Gastrointestinal stromal tumor; CI, Confidence interval
  2. (a) These variables of sex, age, lesion location, lesion size, and echo heterogeneity were included in the multivariable logistic regression analysis. (b)P value is statistically significant. (c) Echo heterogeneity was not described in the original reports for 11 lesions