Fig. 5

The Dose–response relationship among CMI and IR in GSD. The relationship between CMI and IR was simulated by RCS based on the AIC. We adjusted the model fully for age, sex, hypertension, diabetes, CHD, PA, asthma, cancer, smoked, and alcohol use. The red solid line represents the curve fitting between variables, and the shaded area indicates the 95% CI of the fit. CMI, cardiometabolic index; IR, insulin resistance; GSD, gallstone disease; RCS, restricted cubic spline; AIC, Akaike Information Criterion; CHD, coronary heart disease; PA, Physical Activity; CI, confidence interval