Table 3 The noninvasive assessment of the patients with FALD
From: Strain elastography for detecting advanced Fontan-associated liver disease: a retrospective study
Variables | non-aFALD | aFALD | P Value |
|---|---|---|---|
(Serum markers) | |||
 Type IV collagen 7S (ng/mL) | 5.0 (4.3–5.8) | 5.7 (4.8–7.0) | 0.0508 |
 Hyaluronic acid (ng/mL) | 22 (9.5–26.5) | 27 (16.5–44.5) | 0.1124 |
 P-III-P (U/mL) | 11.0 (8.8–13.3) | 11.7 (9.0–13.7) | 0.5816 |
 M2BPGi (C.O.I.) | 0.26 (0.21–0.33) | 0.32 (0.26–0.50) | 0.1033 |
(Noninvasive tests) | |||
 Forns index | 2.60 (1.78–3.86) | 5.35 (4.08–6.35) | 0.0003 |
 FIB-4 index | 0.56 (0.41–0.67) | 1.04 (0.77–1.27) | 0.0001 |
 APRI | 0.41 (0.29–0.47) | 0.56 (0.46–0.79) | 0.0023 |
 MELD | 11.5 (8.1–13.8) | 9.4 (5.5–12.3) | 0.3055 |
 MELD-XI | 5.1 (3.2–9.0) | 5.0 (3.5–9.1) | 0.9029 |
(Elastography) | |||
 LF Index | 1.82 (1.47–2.36) | 2.48 (2.26–2.76) | 0.0008 |
 Vs (m/s) | 1.83 (1.46–2.09) | 2.06 (1.80–2.95) | 0.0970 |