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Table 3 Analysis of the saturation effect of the AST/ALT ratio on 28-day mortality following ICU admission

From: Nonlinear association between AST/ALT ratio and 28-day all-cause mortality following ICU admission in critically ill cirrhotic patients: a retrospective cohort study

Model

OR (95% CI)

P value

Model I: Linear

1.1 (1.0, 1.3)

0.002

Model II: Piecewise Linear

 Inflection point of the AST/ALT ratio

3.6

 

  ≤ 3.6

1.4 (1.2, 1.6)

< 0.001

  > 3.6

1.0 (0.8, 1.1)

0.600

 Log-likelihood ratio test

-

0.011

  1. Model II was adjusted for demographic factors (age, gender, ethnicity) and clinical variables including hypertension, acute kidney injury, hepatorenal syndrome, ventilation status, CRRT, use of vasoactive agents and diuretics, as well as laboratory and scoring parameters such as WBC count, hemoglobin, platelet count, sodium, chloride, SOFA score, and MELD score
  2. Abbreviations: OR odds ratio, CI confidence interval, Ref reference, SOFA Sequential Organ Failure Assessment, MELD Model for End-stage Liver Disease
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BMC Gastroenterology

ISSN: 1471-230X

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