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Table 6 Threshold effect analysis of HbA1c/HDL-C on NAFLD using a linear regression model

From: The HbA1c/HDL-C ratio as a screening indicator of NAFLD in U.S. adults: a cross-sectional NHANES analysis (2017–2020)

Non-Alcoholic Fatty Liver Disease

Adjusted OR (95% CI), P - value

Fitting by the standard linear model

1.203(1.137,1.272) < 0.001

Fitting by the two-piecewise linear model

 

Inflection point

5.743

HbA1c/HDL-C < 5.743

1.323(1.218,1.436) < 0.001

HbA1c/HDL-C > 5.743

1.080(0.992,1.174) 0.075

The predicted values of the equation at the inflection point.

0.646(0.543,0.750)

Log likelihood ratio

0.002

  1. Abbreviations: HbA1c/HDL-C ratio: hemoglobin A1c to high-density lipoprotein cholesterol ratio; OR: Odds ratios; CI: confidence interval