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  1. The non-HDL cholesterol to HDL cholesterol ratio (NHHR) is a novel composite lipid index. However, its relationship with mortality, particularly in individuals with non-alcoholic fatty liver disease (NAFLD), r...

    Authors: Lisha Yang, Jingwen Li, Yilian Xie and Guoqing Qian
    Citation: BMC Gastroenterology 2025 25:288
    Content type: Research Published on:

  2. Drug resistance reflects the evolution of tumors and represents the leading factor behind recurrence and death. Lenvatinib is the first-line therapy for hepatocellular carcinoma (HCC), but its effectiveness is...

    Authors: Jinfeng Wang, Jianfei Shi, Lili Mi, Ning Li, Xin Han, Man Zhao, Xiaoling Duan, Guangjie Han, Jiaojiao Hou and Fei Yin
    Citation: BMC Gastroenterology 2025 25:287
    Content type: Research Published on:

  4. Autoimmune liver diseases (AILDs) are associated with systemic rheumatic diseases (SRDs) and their autoantibodies. This study investigates the prevalence of SRDs and related autoantibodies in AILD patients and...

    Authors: Mohammad Egbaria, Amir Bieber, Abed Mahamid and Rawi Hazzan
    Citation: BMC Gastroenterology 2025 25:282
    Content type: Research Published on:

  5. The aim of this study was to translate the health-related quality-of-life questionnaire EORTC QLQ-LMC21 into Swedish and to test its clinical and psychometric reliability and validity in patients with liver me...

    Authors: Anna Lindhoff Larsson, Peter Holka, Bengt Isaksson, Oskar Hemmingsson, Per Sandström and Bergthór Björnsson
    Citation: BMC Gastroenterology 2025 25:281
    Content type: Research Published on:

  6. The correlation between tumor-specific growth factor (TSGF) and the prognosis of colorectal cancer (CRC)has not been extensively studied. Research was designed to evaluate the potential of TSGF as a predictive...

    Authors: Yanjun Lu, Xinxuan Zhao, Haiyi Liu, Yixun Zhang, Linghong Guo and Lichun Wang
    Citation: BMC Gastroenterology 2025 25:280
    Content type: Research Published on:

  7. Obstructive sleep apnoea (OSA), Non-alcoholic fatty liver disease (NAFLD) and insulin resistance (IR) are interlinked. The aim of our study was to investigate the predictive value of metabolic score for insuli...

    Authors: Min Li, Yujing Wan, Ziyue Wei and Weihong Lin
    Citation: BMC Gastroenterology 2025 25:279
    Content type: Research Published on:

  8. Helicobacter pylori (H. pylori) are classified as a Group 1 carcinogen by the International Agency for Research on Cancer (IARC), highlighting its well-established role in gastric carcinogenesis. While previous s...

    Authors: Zhouhan Wu, Yi Tang, Meiwen Tang, Zhoutong Wu and Yonghui Xu
    Citation: BMC Gastroenterology 2025 25:278
    Content type: Research Published on:

  9. Colorectal cancer (CRC) incidence is rising in Nigeria, with majority of patients presenting with advanced disease. Despite promising results of PD-L1 antibody therapy in clinical trials, efficacy data exclusivel...

    Authors: Felix Emeka Menkiti, Chukwudi Onyeaghana Okani, Igwebuike Victor Onyiaorah, Cornelius Ozobia Ukah, Ifeoma Oluchukwu Menkiti, Eric Chukwudi Ihekwoaba, Odili Aloysius Okoye, Ogochukwu Chioma Ofiaeli and Frank Chinedu Akpuaka
    Citation: BMC Gastroenterology 2025 25:277
    Content type: Research Published on:

  10. Octogenarians constitute a growing number of diagnoses for colorectal cancer. However, the optimal treatment for these increasingly vulnerable octogenarians with colorectal cancer remains a challenging issue. ...

    Authors: Soo Young Oh, Jung Yun Park, Kwan Mo Yang, Seong-A Jeong, Yong Jae Kwon, Yun Tae Jung, Chung Hyeun Ma, Keong Won Yun, Kwang Hyun Yoon, Jae Young Kwak and Chang Sik Yu
    Citation: BMC Gastroenterology 2025 25:276
    Content type: Research Published on:

  11. Adenoma detection rate (ADR) is a key quality indicator in colonoscopy, with low ADRs linked to higher risks of post-colonoscopy colorectal cancers. Feedback to endoscopists has been shown to improve ADRs; how...

    Authors: Ya-Hui Hsu, Chia-Hsin Cheng, Ping-Hung Ko, Chia-Pei Tang, Chih-Wei Huang and Chih-Wei Tseng
    Citation: BMC Gastroenterology 2025 25:275
    Content type: Research Published on:

  12. Insulin resistance (IR) is a crucial mechanism in the pathogenesis and clinical progression of metabolic dysfunction-associated steatotic liver disease (MASLD). This study aimed to examine the relationship bet...

    Authors: Sang Yi Moon, Minkook Son, Yeo Wool Kang, Myeongseok Koh, Jong Yoon Lee and Yang Hyun Baek
    Citation: BMC Gastroenterology 2025 25:274
    Content type: Research Published on:

  13. Helicobacter pylori (H. pylori) infection is a common chronic infection, and there are over half of the global population infected with H. pylori. It is still controversial whether the supplementation of Saccharo...

    Authors: Yi-Zhou Jiang, Kai Ma, Cheng Cui, Zhuo-Ya Li and Xiao-Yong Wang
    Citation: BMC Gastroenterology 2025 25:273
    Content type: Research Published on:

  16. Previous studies on the association between non-skimmed milk consumption and non-alcoholic fatty liver disease (NAFLD) have reported inconsistent findings, with some suggesting an increased risk and others ind...

    Authors: Futao Wu, Fuying Zheng, Xue Li, Danzhu Wu, Honghao Li, Yingyi Zeng, Yan Tang, Side Liu and Aimin Li
    Citation: BMC Gastroenterology 2025 25:270
    Content type: Research Published on:

  17. Acute pancreatitis (AP) is a complex disorder with gallstones being the most common underlying cause. Anatomical variations of gallbladder, cystic duct (CD), common bile duct and main pancreatic duct and their...

    Authors: Ahmet Sukru Alparslan, Serkan Ocal, Osman Cagin Buldukoglu, Galip Egemen Atar, Lutfullah Zahit Koc, Merve Eren Durmus, Serdar Akca, Ferda Akbay Harmandar and Ayhan Hilmi Cekin
    Citation: BMC Gastroenterology 2025 25:269
    Content type: Research Published on:

  18. Gallstones, a global hepatobiliary disorder, are linked to systemic inflammation, lipid disturbances, and metabolic-associated fatty liver disease (MAFLD). This population-based study aims to investigate the a...

    Authors: Xin Feng, Xiangyu Song, Xi’an Yang, Fuxiang Luan, Yufei Gu, Fengyu Zheng, Huahu Guo and Shishi Qiao
    Citation: BMC Gastroenterology 2025 25:268
    Content type: Research Published on:

  20. The NAPOLI 3 trial demonstrated that compared to the nab-paclitaxel and gemcitabine (GemNab) regimen, the NALIRIFOX (5-fluorouracil, leucovorin, liposomal irinotecan, oxaliplatin) regimen can significantly imp...

    Authors: Wenjie Liu, Yuting Fang, Chao Zhang, Midan Xiang, Lijuan Qi, Aijiang Su and Yongkun Sun
    Citation: BMC Gastroenterology 2025 25:266
    Content type: Research Published on:

  21. Cardiometabolic index (CMI) was proposed ten years ago as an indicator combining obesity and dyslipidemia. This study aimed to investigate the relationships between newly modified CMI (MCMI) with non-alcoholic...

    Authors: Yanjun Guo, Wei Su, Lulong Tao, Guoxin Zhang and Kun Wang
    Citation: BMC Gastroenterology 2025 25:265
    Content type: Research Published on:

  22. Gastric cancer (GC) continues to pose a significant global health challenge, particularly in advanced stages where treatment options are severely constrained. Immunotherapy represents a groundbreaking advancem...

    Authors: Rui Wang, Huihui Zeng, Mengting Shi, Yue Wu, Yang Liu and Tiantian Zhang
    Citation: BMC Gastroenterology 2025 25:264
    Content type: Research Published on:

  23. The higher prevalence of non-alcoholic fatty liver disease (NAFLD) in men than women before menopause and the reduced difference post-menopause suggest that sex hormones may influence liver lipid accumulation....

    Authors: Motahare-Sadat Hosseini, Fereshteh Barjesteh, Fereshteh Azedi, Iraj Alipourfard, Zahra Rezaei and Elham Bahreini
    Citation: BMC Gastroenterology 2025 25:263
    Content type: Research Published on:

  24. Subtotal laparoscopic cholecystectomy (LSC) is a rescue procedure in difficult case, retaining all advantages of minimally invasive surgery. The most reputed definition of subtotal cholecystectomy is the remov...

    Authors: Abhijeet Kumar, Bhawani Khanal Designation, Bikash Kumar Sah, Parbat Raj Regmi, Rakesh Kumar Gupta and Suresh Prasad Sah
    Citation: BMC Gastroenterology 2025 25:262
    Content type: Research Published on:

  25. Non-alcoholic fatty liver disease is one of the most common chronic diseases all around the world, which significantly correlates with metabolic disorders and inflammatory cycles. Sarcopenia is a decrease in t...

    Authors: Bahar Arasteh, Sina Hamzehzadeh, Kia Seyed Toutounchi, Zeinab Nikniaz, Leila Amini and Leila Alizadeh
    Citation: BMC Gastroenterology 2025 25:261
    Content type: Research Published on:

  26. The purpose of this research is to evaluate the predictive capabilities of a radiomics model for the Ki67 index and its correlation with prognosis in advanced gastric tubular adenocarcinoma patients.

    Authors: Jiatong Lu, Yong Xiao, Qiushuang Wang, Fangfang Chen, Zhi Zeng, Junfeng Yan, Qiang Li and Qiang Tong
    Citation: BMC Gastroenterology 2025 25:260
    Content type: Research Published on:

  27. Non-alcoholic fatty liver disease (NAFLD) is a global problem strongly interlinked with metabolic syndrome. Insulin resistance (IR) is a key factor both in pathogenesis and in the progression to liver fibrosis...

    Authors: Lubna Kamani, Moneeba Siddiqui and Adeel Rahat
    Citation: BMC Gastroenterology 2025 25:259
    Content type: Research Published on:

  28. This study aimed to analyze the distribution characteristics of infecting microorganisms in the wound tissue of patients with perianal abscess and infection, as well as to identify factors affecting wound heal...

    Authors: Luji Qiao, Hongjian Gao, Yi You and Jinliang Zhu
    Citation: BMC Gastroenterology 2025 25:258
    Content type: Research Published on:

  29. Hepatocellular carcinoma (HCC) has a poor prognosis, especially in elderly HCC patients. A growing number of studies have confirmed that nomogram based on demographic information, pathologic information, and t...

    Authors: Shuyu Liu, Mengyue Zhou, Peng Chen, Xueting Deng, Jiayi Gu and Lin Miao
    Citation: BMC Gastroenterology 2025 25:257
    Content type: Research Published on:

  30. Gastric cancer (GC) is one of the leading causes of cancer-related mortality worldwide, with limited therapeutic options and a poor prognosis, particularly in advanced stages. Glycometabolism, a hallmark of ca...

    Authors: Wanchun Ye, Xiaolei Zhang, Zhongjie Tang, Yufeng Hu, Yuanliang Zheng and Yuping Yuan
    Citation: BMC Gastroenterology 2025 25:256
    Content type: Research Published on:

  31. Metabolic dysfunction-associated fatty liver disease (MAFLD) is a common chronic liver disease and represents a significant public health issue. Nevertheless, current risk stratification methods remain inadequ...

    Authors: Liqiong Huang, Yu Luo, Li Zhang, Mengqi Wu and Lirong Hu
    Citation: BMC Gastroenterology 2025 25:255
    Content type: Research Published on:

  32. Biliary disorders are a major health concern in Nigeria, where magnetic resonance cholangiopancreatography (MRCP), a non-invasive imaging tool offering effective duct visualization without radiation, is emergi...

    Authors: Nuraddeen Mukhtar Rabiu, Abbas Rabiu Muhammad, Ahmad Bashir Umar, Sambo-Donga Donzomga, Ibrahim Umar Garzali, Suwaid Mohammed Abba and Anas Ismail
    Citation: BMC Gastroenterology 2025 25:254
    Content type: Research Published on:

  33. and aims: Although abdominal drainage tubes have been widely used to treat cholelithiasis, complications still affect patients’ prognoses. There is no Standardized Nursing Process (SNP) for abdominal drainage tub...

    Authors: Wenhui Shi, Yan Huang, Zipeng Xu, Xinyi Huang, Genxi Tong, Jiamei Lin, Yanan Zhou, Qinyan Yang and Chaobo Chen
    Citation: BMC Gastroenterology 2025 25:253
    Content type: Research Published on:

  35. Peroral endoscopic myotomy (POEM) is an increasingly utilized endoscopic therapy for achalasia. When undergoing esophagogastroduodenoscopy (EGD), patients with a diagnosis of achalasia may receive endotracheal...

    Authors: Julia D. Liberto, Ross Dierkhising, Diana L. Snyder, Karthik Ravi, Jeffrey A. Alexander and D. Chamil Codipilly
    Citation: BMC Gastroenterology 2025 25:251
    Content type: Research Published on:

  37. Gallbladder and biliary tract diseases pose a significant global health burden, yet comprehensive analyses of their long-term epidemiological trends and future projections remain limited. This study aims to ex...

    Authors: Fangyi Dai, Yuzhou Cai, Shangjin Yang, Jingyang Zhang and Yong Dai
    Citation: BMC Gastroenterology 2025 25:249
    Content type: Research Published on:

  38. Perforated peptic ulcer (PPU) is a surgical emergency condition associated with substantial mortality and morbidity. Despite scattered studies, there exists a gap in comprehensive evidence on management outcom...

    Authors: Destaw Endeshaw, Ousman Adal, Abiyu Abadi Tareke, Natnael Kebede, Amare Mebrat Delie, Eyob Ketema Bogale, Tadele Fentabel Anagaw, Misganaw Guadie Tiruneh and Eneyew Talie Fenta
    Citation: BMC Gastroenterology 2025 25:248
    Content type: Systematic Review Published on:

  39. Plasma lipid homeostasis is pivotal in maintaining intestinal health. Inflammatory bowel disease (IBD), encompassing ulcerative colitis (UC) and Crohn’s disease (CD) as distinct subtypes, manifests unique meta...

    Authors: Hang Lei, Yuhong Jiang, Zhe Chen, Jiaqi Yao, Wenjun Ma, Yiqi Huang, Pengcheng Zhang, Zhijun Xie, Lv Zhu and Wenfu Tang
    Citation: BMC Gastroenterology 2025 25:247
    Content type: Research Published on:

  40. Perianal abscess (PA) is a complication of infection in patients with hematologic malignancies. However, the simultaneous occurrence of neutropenia and increased susceptibility to bleeding pose significant cha...

    Authors: Xun Wang, Lili Pan, Yanyan Qiu and Tingbo Liu
    Citation: BMC Gastroenterology 2025 25:246
    Content type: Research Published on:

  41. Probiotic supplementation has been proposed as a preventive measure for necrotizing enterocolitis (NEC) in preterm infants. This umbrella meta-analysis assesses the effects of probiotics, including single-stra...

    Authors: Jiaju Han, Yufeng Ren, Peini Zhang, Chengfeng Fang, Leilei Yang, Shenkang Zhou and Zhiqing Ji
    Citation: BMC Gastroenterology 2025 25:245
    Content type: Systematic Review Published on:

  42. Cholecystectomy is one of the most common surgical procedures for the treatment of diseases associated with gallstones, and the incidence of post-cholecystectomy diarrhea (PCD) has attracted attention in recen...

    Authors: Fengjiao Mao, Daya Zhang, Xianfeng Huang, Da Li, Wenrui Chen, Fan Zeng, Chen Chen, Shimei Huang, Yanting Lv, Yuliang Huang, Runyu Chen, Ying Mo, Qiuli Nie, Shuo Zhou, Xiaodong Zhang, Qicen Yao…
    Citation: BMC Gastroenterology 2025 25:244
    Content type: Research Published on:

  43. Endoscopic retrograde cholangiopancreatography (ERCP) is important in the management of pancreatobiliary diseases and requires fluoroscopy resulting in radiation exposure to those involved. ERCP is performed i...

    Authors: Daniel Marino, Kanhai Farrakhan, Ethan Pearlstein, Joao Filipe Monteiro, Sohum Patwa, Mouhand Mohamed, Rei Mitsuyama, Savan Kothadia, Aastha Chokshi, Harlan Rich and Akwi Asombang
    Citation: BMC Gastroenterology 2025 25:243
    Content type: Research Published on:

  44. Colon cancer is one of the most prevalent malignancies globally. Anthropometric data are widely accessible. However, numerous anthropometric indicators exist, and no study has identified the most reliable pred...

    Authors: Kaihao Wang, Anlei Wang, Shaozu Wang, Zhijiang Luo, Yazhao Gong, Xiaoliang Hao, Guanglei Yang and Shuqing Xu
    Citation: BMC Gastroenterology 2025 25:242
    Content type: Research Published on:

  45. To evaluate the correlation and consistency between hepatic venous pressure gradient(F-HVPG) calculated as the wedged hepatic venous pressure (WHVP) minus free hepatic venous pressure (FHVP), I-HVPG calculated...

    Authors: Rufeng Chen, Yaozu Liu, Li Ma, Wen Zhang, Yongjie Zhou, Minjie Yang, Jiaze Yu, Zhiping Yan, Jingqin Ma and Jianjun Luo
    Citation: BMC Gastroenterology 2025 25:241
    Content type: Research Published on:

  46. The relationship between KRAS mutations and the risk of venous thromboembolism (VTE) recurrence in metastatic colorectal cancer (mCRC) patients with established cancer-associated thrombosis (CAT) remains uncertai...

    Authors: Zhikun Liang, Xiaoyan Huang, Jieling Mao, Jingwen Xie, Xiaoyan Li and Li Qin
    Citation: BMC Gastroenterology 2025 25:240
    Content type: Research Published on:

  47. Our research aims to explore the effects of different exercise on liver function and bile acid in patients with non-alcoholic fatty liver disease (NAFLD), to identify the most beneficial exercise modalities fo...

    Authors: Jiasen Shi, Junchao Cui, Tianlei Zheng, Xiaoping Han, Bin Wang, Wenjing Wang, Chenggang Zhu, Chenle Fang, Xueyan Zhou, Ning Cong, Xiaoxing Yin and Qiang Yang
    Citation: BMC Gastroenterology 2025 25:239
    Content type: Research Published on:

  48. Metabolic score for visceral fat (METS-VF) as an effective marker of visceral obesity has been correlated with non-alcoholic fatty liver disease (NAFLD). This study aims to explore the correlation between METS...

    Authors: Chunming Xie, Xianpei Chen, Jiakun Zhang, Xueqing Jiang, Jing Xu and Hao Lin
    Citation: BMC Gastroenterology 2025 25:238
    Content type: Research Published on:

  49. Gastric stromal tumors (GSTs) and gastric leiomyomas (GLs) represent the primary subtypes of gastric submucosal tumors (SMTs) characterized by distinct biological characteristics and treatment modalities. The ...

    Authors: Ruifeng Duan, Liwei Duan, Xin Chen, Min Liu, Xiangyi Song and Lijuan Wei
    Citation: BMC Gastroenterology 2025 25:237
    Content type: Research Published on:

  50. Extrahepatic cholangiocarcinoma (eCCA) is a rare but refractory cancer with dense desmoplasia. Prognosis-associated stromal cells in eCCA remain poorly characterized. Here, we profiled the tumor cellular compo...

    Authors: Chen Ni, Rulin Hua, Yuanyuan Yang, Jialu Liang, Wentao Liu, Linlin Wang, Xiaohan Yao, Anqi Li, Long Yu, Ruo Feng, Dekang Lv, Zhihai Qin and Wenlong Zhai
    Citation: BMC Gastroenterology 2025 25:235
    Content type: Research Published on:
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BMC Gastroenterology

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